Paul Hrvatin

Identification and Optimization of Pteridinone Toll-like Receptor 7 (TLR7) Agonists for the Oral Treatment of Viral Hepatitis

Paul A. Roethle, Ryan M. L. McFadden, Hong Yang et al. · Journal of Medicinal Chemistry · 2013 · 67 citations · Full text

Selective Alternatives, Immunology, Immune Regulation +24

Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 2: Optimization of BX-517

Imadul Islam, Greg Brown, Judi Bryant et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 41 citations · Full text

Phosphoinositide-dependent Kinase-1, Drug Target, Biochemistry +7

A novel inhibitor of activated thrombin-activatable fibrinolysis inhibitor (TAFIa) – Part I: Pharmacological characterization

Lei Zhao, Mariko Nagashima, Jon Vincelette et al. · Thrombosis and Haemostasis · 2007 · 31 citations

Structures of potent selective peptide mimetics bound to carboxypeptidase B

Marc Adler, Brad O. Buckman, Judi Bryant et al. · Acta Crystallographica Section D Biological Crystallography · 2008 · 21 citations

Protein Assembly, Peptide Engineering, Molecular Biology +17