Richard L. Darley

Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling

Paul S. Hole, Joanna Zabkiewicz, Chinmay Munje et al. · Blood · 2013 · 224 citations

CD200 expression suppresses natural killer cell function and directly inhibits patient anti-tumor response in acute myeloid leukemia

Steven Coles, Eddie C. Y. Wang, Stephen Man et al. · Leukemia · 2011 · 172 citations · Full text

Hematological Malignancy, Tumor Biology, Cancer Immunosurveillance +13

Ras-induced reactive oxygen species promote growth factor–independent proliferation in human CD34+ hematopoietic progenitor cells

Paul S. Hole, Lorna Pearn, Amanda J. Tonks et al. · Blood · 2009 · 131 citations

Transcriptional dysregulation mediated by RUNX1-RUNX1T1 in normal human progenitor cells and in acute myeloid leukaemia

Alex Tonks, Lorna Pearn, M Musson et al. · Leukemia · 2007 · 89 citations

Hematological Malignancy, Mixed-phenotype Acute Leukemia, Malignant Blood Disorder +8

Reactive Oxygen Species Drive Proliferation in Acute Myeloid Leukemia via the Glycolytic Regulator PFKFB3

Andrew Robinson, Goitseone L. Hopkins, Namrata Rastogi et al. · Cancer Research · 2019 · 86 citations · Full text