Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

Pawel Buczkowicz, Christine M. Hoeman, Patricia Rakopoulos, +49

Nature Genetics

Neuro-oncologyRadiation OncologyEngineeringTumor HeterogeneityMedicine +8

Integrated Molecular and Clinical Analysis of 1,000 Pediatric Low-Grade Gliomas

Scott Ryall, Michal Zápotocký, Kohei Fukuoka, +42

Cancer Cell

Neuro-oncologyTumoral PathologyPediatric Brain TumorsOncologyPediatric Neurosurgery +11

Characterisation of retinoblastomas without RB1 mutations: genomic, gene expression, and clinical studies

Diane Rushlow, Berber M. Mol, Jennifer Y. Kennett, +22

The Lancet Oncology

Cell Cycle-Regulated Association of E2F1 and Sp1 Is Related to Their Functional Interaction

Shiaw‐Yih Lin, Adrian R. Black, Dusan Kostic, +3

Molecular and Cellular Biology

GeneticsTheir Functional InteractionCell CycleTranscriptional RegulationSignaling Pathway +17

Reconstitution of the response to leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor in hepatoma cells.

Heinz Baumann, Steven F. Ziegler, Bruce Mosley, +3

Journal of Biological Chemistry

Targeted detection of genetic alterations reveal the prognostic impact of H3K27M and MAPK pathway aberrations in paediatric thalamic glioma

Scott Ryall, Rahul Krishnatry, Anthony Arnoldo, +12

Acta Neuropathologica Communications

Interaction of the 72-kilodalton human cytomegalovirus IE1 gene product with E2F1 coincides with E2F-dependent activation of dihydrofolate reductase transcription

Michael Margolis, Sanja Pajovic, Emily L. Wong, +4

Journal of Virology

Viral ReplicationE2f-dependent ActivationGeneticsMolecular BiologyDhfr Promoter +17

Kinesin family member 14: An independent prognostic marker and potential therapeutic target for ovarian cancer

Brigitte L. Thériault, Sanja Pajovic, Marcus Q. Bernardini, +2

International Journal of Cancer

Potential Therapeutic TargetKif14 ExpressionOncogenic AgentIndependent Prognostic MarkerMedicine +12

Identification of a Viral Kinase That Phosphorylates Specific E2Fs and Pocket Proteins

Sanja Pajovic, Emily L. Wong, Adrian R. Black, +1

Molecular and Cellular Biology

E2f SitePocket ProteinsMolecular BiologyViral Structural ProteinCancer-associated Virus +21

ATM Regulates 3-Methylpurine-DNA Glycosylase and Promotes Therapeutic Resistance to Alkylating Agents

Sameer Agnihotri, Kelly Burrell, Pawel Buczkowicz, +18

Cancer Discovery