Kathy Manchulenko

Enhancing Antibody Fc Heterodimer Formation through Electrostatic Steering Effects

Kannan Gunasekaran, Martin Pentony, Min Shen et al. · Journal of Biological Chemistry · 2010 · 284 citations · Full text

Pharmacy, Biotechnology, Immunology +17

A Novel Antibody Engineering Strategy for Making Monovalent Bispecific Heterodimeric IgG Antibodies by Electrostatic Steering Mechanism

Zhi Liu, Esther Leng, Kannan Gunasekaran et al. · Journal of Biological Chemistry · 2015 · 75 citations · Full text

Pharmacy, Biotechnology, Immunology +16

MEDI0639: A Novel Therapeutic Antibody Targeting Dll4 Modulates Endothelial Cell Function and Angiogenesis <i>In Vivo</i>

David W. Jenkins, Sarah J. Ross, Margaret H. Veldman-Jones et al. · Molecular Cancer Therapeutics · 2012 · 51 citations

Medicine, Cancer Biology, Oncology +15

Pharmacology of <scp>AMG</scp> 181, a human anti‐α₄β₇ antibody that specifically alters trafficking of gut‐homing <scp>T</scp> cells

WJ Pan, H. Hsu, WA Rees et al. · British Journal of Pharmacology · 2013 · 38 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Remediating agitation-induced antibody aggregation by eradicating exposed hydrophobic motifs

Rutilio H. Clark, Ramil F. Latypov, Cyr De Imus et al. · mAbs · 2014 · 19 citations · Full text

Pharmacy, Bioinformatics, Molecular Biology +17