A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

Norman Sachs, Joep de Ligt, Oded Kopper, +28

Cell

Breast OncologyOncologyEngineeringBiobankTumor Heterogeneity +9

Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C

Rachel Ulferts, S.M. de Boer, Lonneke van der Linden, +10

Antimicrobial Agents and Chemotherapy

Molecular VirologyIdentified PirlindoleMedicinePrestwick Chemical LibraryImmunology +9

An Image-Based miRNA Screen Identifies miRNA-135s As Regulators of CNS Axon Growth and Regeneration by Targeting Krüppel-like Factor 4

Eljo Y. van Battum, Marieke G. Verhagen, Vamshidhar R. Vangoor, +11

Journal of Neuroscience

Aurora A, MCAK, and Kif18b promote Eg5-independent spindle formation

Roy G. H. P. van Heesbeen, Jonne A. Raaijmakers, Marvin E. Tanenbaum, +6

Chromosoma

The glucocorticoid mometasone furoate is a novel FXR ligand that decreases inflammatory but not metabolic gene expression

Ingrid T.G.W. Bijsmans, Chiara Guercini, José M. Ramos Pittol, +7

Scientific Reports

High-content screening of peptide-based non-viral gene delivery systems

Markus de Raad, Erik A. Teunissen, Daphne Lelieveld, +2

Journal of Controlled Release

EngineeringPeptide EngineeringSynthetic BiologyDrug Delivery SystemsPeptide Therapeutics +5

Discovery of Small Molecules That Induce Lysosomal Cell Death in Cancer Cell Lines Using an Image-Based Screening Platform

Romina J. Pagliero, Diego S. D’Astolfo, Daphne Lelieveld, +6

Assay and Drug Development Technologies

ApoptosisImage-based Screening PlatformCell DeathAnti-cancer AgentLcd Inducers +20

HC StratoMineR: A Web-Based Tool for the Rapid Analysis of High-Content Datasets

Wienand A. Omta, Roy G. van Heesbeen, Romina J. Pagliero, +11

Assay and Drug Development Technologies

EngineeringInteractive Data ExplorationData ExplorationHigh-content DatasetsNovel Data Source +18

High-Throughput Screening Identifies Idasanutlin as a Resensitizing Drug for Venetoclax-Resistant Neuroblastoma Cells

Lindy Vernooij, Laurel T. Bate-Eya, Lindy K. Alles, +13

Molecular Cancer Therapeutics

Genome-wide RNAi screen for synthetic lethal interactions with the C. elegans kinesin-5 homolog BMK-1

André F. Maia, Marvin E. Tanenbaum, Matilde Galli, +6

Scientific Data