A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

Robert Pejchal, Katie J. Doores, Laura M. Walker, +28

Science

ImmunologyGlycobiologyMolecular BiologyImmunodominanceImmunotherapeutics +16

Characterization of H7N9 influenza A viruses isolated from humans

Tokiko Watanabe, Maki Kiso, Satoshi Fukuyama, +47

Nature

Viral EvolutionVirologyMicrobiologyA VirusesMedicine

Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers

Emilia Falkowska, Khoa Le, Alejandra Ramos, +27

Immunity

Cleaved Envelope TrimersVirus StructureHuman RetrovirusGlycobiologyImmunology +8

Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein

Wentao Li, Ruben J. G. Hulswit, Ivy Widjaja, +14

Proceedings of the National Academy of Sciences

Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120

Leopold Kong, Jeong Hyun Lee, Katie J. Doores, +24

Nature Structural & Molecular Biology

A General Strategy for the Chemoenzymatic Synthesis of Asymmetrically Branched <i>N</i> -Glycans

Zhen Wang, Zoeisha S. Chinoy, Shailesh Ambre, +6

Science

Chemoenzymatic SynthesisDiverse LibrariesGeneral StrategyBioorganic ChemistryEngineering +17

Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans

Jean‐Philippe Julien, Devin Sok, Reza Khayat, +19

PLoS Pathogens

A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure

Jeong Hyun Lee, Raiees Andrabi, Ching-Yao Su, +15

Immunity

A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine

Nicholas C. Wu, Seth J. Zost, Andrew J. Thompson, +6

PLoS Pathogens

ImmunologyFlu VaccinationVaccine HesitancyViral Structural ProteinInfluenza Vaccines +17

Microbial glycan microarrays define key features of host-microbial interactions

Sean R. Stowell, Connie M. Arthur, Ryan McBride, +11

Nature Chemical Biology

Microbial Glycan MicroarraysHost-microbe InteractionsMicrobial InteractionsMicrobiologyHost-microbe Interaction +4