Dominic Helm

The target landscape of clinical kinase drugs

Susan Klaeger, Stephanie Heinzlmeir, Mathias Wilhelm et al. · Science · 2017 · 845 citations · Full text

Tumor Biology, Proteomicsdb Database, Drug Target +14

The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice

Alida Kindt, Gerhard Liebisch, Thomas Clavel et al. · Nature Communications · 2018 · 268 citations · Full text

Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP

Sindhuja Sridharan, Nils Kurzawa, Thilo Werner et al. · Nature Communications · 2019 · 268 citations · Full text

Pervasive Protein Thermal Stability Variation during the Cell Cycle

Isabelle Becher, Amparo Andrés‐Pons, Natalie Romanov et al. · Cell · 2018 · 243 citations · Full text

Protein Function, Cell Division, Protein Folding +7

DMSO enhances electrospray response, boosting sensitivity of proteomic experiments

Hannes Hahne, Fiona Pachl, Benjamin Ruprecht et al. · Nature Methods · 2013 · 234 citations · Full text

Proteomic Technology, Biochemistry, Medicine +6