Niamh Spence

DNA haplotype analysis of Huntington disease reveals clues to the origins and mechanisms of CAG expansion and reasons for geographic variations of prevalence

Ferdinando Squitieri, Susan E. Andrew, Y. Paul Goldberg et al. · Human Molecular Genetics · 1994 · 183 citations

Life Sciences, Genetics, Molecular Genetics +16

Safety, immunogenicity, and reactogenicity of BNT162b2 and mRNA-1273 COVID-19 vaccines given as fourth-dose boosters following two doses of ChAdOx1 nCoV-19 or BNT162b2 and a third dose of BNT162b2 (COV-BOOST): a multicentre, blinded, phase 2, randomised trial

Alasdair Munro, Shuo Feng, Leila Janani et al. · The Lancet Infectious Diseases · 2022 · 177 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +16

Sex-dependent mechanisms for expansions and contractions of the CAG repeat on affected Huntington disease chromosomes.

B Kremer, E. Almqvist, Jane Theilmann et al. · PubMed · 1995 · 160 citations

Life Sciences, Genetics, Molecular Genetics +11

Efficacy, safety, and immunogenicity of a booster regimen of Ad26.COV2.S vaccine against COVID-19 (ENSEMBLE2): results of a randomised, double-blind, placebo-controlled, phase 3 trial

Karin Hardt, An Vandebosch, Jerald Sadoff et al. · The Lancet Infectious Diseases · 2022 · 88 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +14

Somatic mosaicism in sperm is associated with intergenerational (CAG)_n changes in Huntington disease

H. Telenius, E. Almqvist, B Kremer et al. · Human Molecular Genetics · 1995 · 82 citations

Life Sciences, Genetics, Molecular Genetics +16