J. Kempeni

Increased serum levels of tumor necrosis factor alpha precede major complications of bone marrow transplantation [see comments]

Ernst Holler, HJ Kolb, A Möller et al. · Blood · 1990 · 580 citations · Full text

Medicine, Hematology, Immunology +9

Assessment of the safety and efficacy of the monoclonal anti-tumor necrosis factor antibody-fragment, MAK 195F, in patients with sepsis and septic shock

Konrad Reinhart, Carola Wiegand-Lohnert, Friedrich Grimminger et al. · Critical Care Medicine · 1996 · 364 citations

Veterinary Medicine, Immunology, Pharmacology +13

Randomized, placebo-controlled trial of the anti-tumor necrosis factor antibody fragment afelimomab in hyperinflammatory response during severe sepsis: The RAMSES Study

Konrad Reinhart, T. Menges, Bengt Gårdlund et al. · Critical Care Medicine · 2001 · 261 citations

Veterinary Medicine, Immunology, Pharmacotherapy +17

A single dose, placebo controlled study of the fully human anti-tumor necrosis factor-alpha antibody adalimumab (D2E7) in patients with rheumatoid arthritis.

Alfons A den Broeder, Leo van de Putte, Rolf Rau et al. · PubMed · 2002 · 195 citations

Pharmacy, Pharmacology, Pharmacotherapy +17

Phase I study of recombinant human tumor necrosis factor ? in advanced malignant disease

Thomas Moritz, N. Niederle, J. M. Baumann et al. · Cancer Immunology Immunotherapy · 1989 · 98 citations · Full text

Medicine, Immunology, Oncology +10