Grace H. McGregor

2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer

Arnaud Blomme, Catriona A. Ford, Ernest Mui et al. · Nature Communications · 2020 · 189 citations · Full text

Medicine, Oncology, Pharmacology +17

Insulin-regulated serine and lipid metabolism drive peripheral neuropathy

Michal K. Handzlik, Jivani M. Gengatharan, Katie Frizzi et al. · Nature · 2023 · 169 citations · Full text

Medicine, Biochemistry, Endocrinology +17

Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix

Emily Kay, Karla Paterson, Carla Riera‐Domingo et al. · Nature Metabolism · 2022 · 154 citations · Full text

Medicine, Cancer Biology, Oncology +16

Mevalonate Pathway Provides Ubiquinone to Maintain Pyrimidine Synthesis and Survival in p53-Deficient Cancer Cells Exposed to Metabolic Stress

Irem Kaymak, Carina R. Maier, Werner Schmitz et al. · Cancer Research · 2019 · 89 citations · Full text

Life Sciences, Cell Biology, Oncology +17

Inter-organelle cross-talk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress

Ramya S. Kuna, Avi Kumar, Karl A. Wessendorf-Rodriguez et al. · Science Advances · 2023 · 57 citations · Full text

Life Sciences, Physiology, Metabolic Physiology +1