Deborah E. Seifert

The extracellular matrix glycoprotein ADAMTSL2 is increased in heart failure and inhibits TGFβ signalling in cardiac fibroblasts

Karoline Bjarnesdatter Rypdal, Pugazendhi M Erusappan, Arne Olav Melleby et al. · Scientific Reports · 2021 · 46 citations · Full text

Life Sciences, Cardiology, Cell Biology +17

Proteomics identifies a convergent innate response to infective endocarditis and extensive proteolysis in vegetation components

Daniel R. Martin, James Witten, Carmela D. Tan et al. · JCI Insight · 2020 · 36 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

ADAMTSL3 knock-out mice develop cardiac dysfunction and dilatation with increased TGFβ signalling after pressure overload

Karoline Bjarnesdatter Rypdal, Arne Olav Melleby, Emma Robinson et al. · Communications Biology · 2022 · 20 citations · Full text

Life Sciences, Cardiology, Molecular Biology +15

Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development

Timothy J. Mead, Sumit Bhutada, Simon J. Foulcer et al. · Matrix Biology · 2024 · 12 citations · Full text

Life Sciences, Developmental Biology, Molecular Biology +15