L. Cohen

Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors

Richard O. Snyder, Carol H. Miao, G. Patijn et al. · Nature Genetics · 1997 · 585 citations

Pharmacy, Genetics, Molecular Biology +13

Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte–macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma

Robert J. Soiffer, Thomas J. Lynch, Martin Mihm et al. · Proceedings of the National Academy of Sciences · 1998 · 579 citations

Medicine, Immunology, Oncology +17

Induction of immunity to prostate cancer antigens: results of a clinical trial of vaccination with irradiated autologous prostate tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor using ex vivo gene transfer.

Jonathan W. Simons, Bahar Mikhak, Ju-Fay Chang et al. · PubMed · 1999 · 468 citations

Medicine, Immunology, Oncology +17

Bioactivity of Autologous Irradiated Renal Cell Carcinoma Vaccines Generated by Ex Vivo Granulocyte-Macrophage Colony-Stimulating Factor Gene Transfer

J.W. Simons, Elizabeth M. Jaffee, C. Weber et al. · The Journal of Urology · 1998 · 414 citations

Medicine, Immunology, Oncology +13

Prolonged production of NADPH oxidase-corrected granulocytes after gene therapy of chronic granulomatous disease

Harry L. Malech, Phillip B. Maples, Narda Whiting‐Theobald et al. · Proceedings of the National Academy of Sciences · 1997 · 344 citations

Medicine, Hematology, Immunology +16