William Meadows

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

John A. Todd, Neil Walker, Jason D. Cooper et al. · Nature Genetics · 2007 · 1.5K citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions

Seema Qamar, Guo-Zhen Wang, Suzanne J. Randle et al. · Cell · 2018 · 944 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function

Tetsuro Murakami, Seema Qamar, Julie Qiaojin Lin et al. · Neuron · 2015 · 920 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether

Ya-Cheng Liao, Michael S. Fernandopulle, G.Z. Wang et al. · Cell · 2019 · 549 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Structural Interactions between Inhibitor and Substrate Docking Sites Give Insight into Mechanisms of Human PS1 Complexes

Yi Li, Stephen Hsueh-Jeng Lu, Ching‐Ju Tsai et al. · Structure · 2013 · 60 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17