Ryan Golhar

Tumor Mutational Burden and Efficacy of Nivolumab Monotherapy and in Combination with Ipilimumab in Small-Cell Lung Cancer

Matthew D. Hellmann, Margaret K. Callahan, Mark M. Awad et al. · Cancer Cell · 2018 · 894 citations · Full text

Medicine, Oncology, Pharmacotherapy +16

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming

Martin Picard, Jiangwen Zhang, Saege Hancock et al. · Proceedings of the National Academy of Sciences · 2014 · 305 citations

Life Sciences, Genetics, Molecular Biology +16

Increased Frequency of De Novo Copy Number Variants in Congenital Heart Disease by Integrative Analysis of Single Nucleotide Polymorphism Array and Exome Sequence Data

Joseph Glessner, Alexander G. Bick, Kaoru Ito et al. · Circulation Research · 2014 · 277 citations

Life Sciences, Genetics, Molecular Genetics +17

Circulating T Cell Subpopulations Correlate With Immune Responses at the Tumor Site and Clinical Response to PD1 Inhibition in Non-Small Cell Lung Cancer

Nataly Manjarrez‐Orduño, Laurence Ménard, Selena Kansal et al. · Frontiers in Immunology · 2018 · 129 citations · Full text

Life Sciences, Immunology, Oncology +17

Whole-genome DNA/RNA sequencing identifies truncating mutations in RBCK1 in a novel Mendelian disease with neuromuscular and cardiac involvement

Kai Wang, Cecilia Kim, Jonathan P. Bradfield et al. · Genome Medicine · 2013 · 96 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17