Laurence J Howe

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

Jie Zheng, A. Mesut Erzurumluoglu, Benjamin Elsworth et al. · Bioinformatics · 2016 · 1K citations · Full text

Public Health, Biostatistics, Genetics +14

Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses

Ben Brumpton, Eleanor Sanderson, Fernando Pires Hartwig et al. · Nature Communications · 2020 · 420 citations · Full text

Public Health, Biostatistics, Genetics +13

UK phenomics platform for developing and validating electronic health record phenotypes: CALIBER

Spiros Denaxas, Arturo González-Izquierdo, Kenan Direk et al. · Journal of the American Medical Informatics Association · 2019 · 254 citations · Full text

Medicine, Biomedical Informatics, Health Informatics +17

Whole-genome sequencing of 490,640 UK Biobank participants

Keren Carss, Bjarni V. Halldórsson, Liping Hou et al. · Nature · 2025 · 93 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases

Ben Brumpton, Eleanor Sanderson, Fernando Pires Hartwig et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2019 · 77 citations · Full text

Public Health, Biostatistics, Genetics +10