Jian Yang

Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma

Yongping Cui, Hongyan Chen, Ruibin Xi et al. · Cell Research · 2020 · 318 citations · Full text

Medicine, Genetics, Oncology +15

The UK10K project identifies rare variants in health and disease

Klaudia Walter, Josine L. Min, Jie Huang et al. · Kölner Universitäts PublikationsServer (Universität zu Köln) · 2015 · 299 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action

Brigitte Ganter, Stuart Tugendreich, Cecelia I. Pearson et al. · Journal of Biotechnology · 2005 · 287 citations

Pharmacy, Bioinformatics, Toxicology +16

Near-infrared upconversion–activated CRISPR-Cas9 system: A remote-controlled gene editing platform

Yongchun Pan, Jingjing Yang, Xiaowei Luan et al. · Science Advances · 2019 · 270 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +14

Multi-region sequencing unveils novel actionable targets and spatial heterogeneity in esophageal squamous cell carcinoma

Ting Yan, Heyang Cui, Yong Zhou et al. · Nature Communications · 2019 · 150 citations · Full text

Medicine, Immunology, Oncology +17