Hellen Jumo

AP-4-mediated axonal transport controls endocannabinoid production in neurons

Alexandra K. Davies, Julian E. Alecu, M. L. ZIEGLER et al. · Nature Communications · 2022 · 55 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

High-content screening identifies a small molecule that restores AP-4-dependent protein trafficking in neuronal models of AP-4-associated hereditary spastic paraplegia

Afshin Saffari, Barbara Brechmann, Cedric Böger et al. · Nature Communications · 2024 · 22 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +13

ALDH5A1-deficient iPSC-derived excitatory and inhibitory neurons display cell type specific alterations

Wardiya Afshar Saber, Nicole A. Teaney, Kellen D. Winden et al. · Neurobiology of Disease · 2023 · 20 citations · Full text

Life Sciences, Genetics, Neuroscience +17

High-throughput imaging of ATG9A distribution as a diagnostic functional assay for adaptor protein complex 4-associated hereditary spastic paraplegia

Darius Ebrahimi‐Fakhari, Julian E. Alecu, Barbara Brechmann et al. · Brain Communications · 2021 · 19 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Functional validation of novel variants in <scp><i>B4GALNT1</i></scp> associated with early‐onset complex hereditary spastic paraplegia with impaired ganglioside synthesis

Julian E. Alecu, Yuhsuke Ohmi, Robiul Hasan Bhuiyan et al. · American Journal of Medical Genetics Part A · 2022 · 13 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17