Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells

Diego Balboa, Tom Barsby, Väinö Lithovius, +22

Nature Biotechnology

Synchronous oscillations of cytoplasmic Ca2+ and insulin release in glucose-stimulated pancreatic islets.

Peter Bergsten, Eva Grapengiesser, Erik Gylfe, +2

Journal of Biological Chemistry

Pancreas TransplantationCellular PhysiologyInsulin SignalingSocial SciencesRapid Islet Oscillations +17

Oscillations of cyclic AMP in hormone-stimulated insulin-secreting β-cells

Oleg Dyachok, Y. Isakov, Jenny Sågetorp, +1

Nature

Molecular PhysiologySignal TransductionEndocrine MechanismPhysiologyCyclic Amp +4

Increased Melatonin Signaling Is a Risk Factor for Type 2 Diabetes

Cecilia Nagorny, Pratibha Singh, Hedvig Bennet, +20

Cell Metabolism

SleepMedicineInsulin ManagementPhysiologyDiabetes +8

Glucose-Induced Cyclic AMP Oscillations Regulate Pulsatile Insulin Secretion

Oleg Dyachok, Olof Idevall‐Hagren, Jenny Sågetorp, +6

Cell Metabolism

Molecular PhysiologySignal TransductionBiochemistryInsulin ManagementPhysiology +5

Glucose- and Hormone-Induced cAMP Oscillations in α- and β-Cells Within Intact Pancreatic Islets

Geng Tian, Stellan Sandler, Erik Gylfe, +1

Diabetes

Origin of slow and fast oscillations of Ca²⁺ in mouse pancreatic islets

Yi‐Jia Liu, Anders Tengholm, Eva Grapengiesser, +2

The Journal of Physiology

Glucose induces oscillatory Ca2+ signalling and insulin release in human pancreatic beta cells

Bo Hellman, Erik Gylfe, Peter Bergsten, +6

Diabetologia

Signal TransductionMolecular PhysiologyInsulin ManagementPhysiologyDiabetes +7

In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis

Volodymyr Petrenko, Nikhil R. Gandasi, Daniel Sage, +3

Proceedings of the National Academy of Sciences

Glucagon ExocytosisInsulin SignalingInsulin DeliveryMetabolic SignalingCell Signaling +15

Paracrine control of α-cell glucagon exocytosis is compromised in human type-2 diabetes

Muhmmad Omar‐Hmeadi, Per-Eric Lund, Nikhil R. Gandasi, +2

Nature Communications