Chang‐En Yu

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Céline Bellenguez, Fahri Küçükali, Iris E. Jansen et al. · Nature Genetics · 2022 · 2.5K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Rebecca Sims, Sven J. van der Lee, Adam C. Naj et al. · Nature Genetics · 2017 · 1.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +12

TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis

Vivianna M. Van Deerlin, James B. Leverenz, Lynn M. Bekris et al. · The Lancet Neurology · 2008 · 720 citations

Life Sciences, Neurology, Neuroscience +15

Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

Eric M. Reiman, Joseph F. Arboleda‐Velásquez, Yakeel T. Quiroz et al. · Nature Communications · 2020 · 490 citations · Full text

Medicine, Genetics, Neurology +17

Assessment of the genetic variance of late-onset Alzheimer's disease

Perry G. Ridge, Kaitlyn B. Hoyt, Kevin L. Boehme et al. · Neurobiology of Aging · 2016 · 255 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17