Amy Shen

Decreasing lactate level and increasing antibody production in Chinese Hamster Ovary cells (CHO) by reducing the expression of lactate dehydrogenase and pyruvate dehydrogenase kinases

Meixia Zhou, Yongping Crawford, Domingos Ng et al. · Journal of Biotechnology · 2011 · 147 citations

Animal Physiology, Pyruvate Dehydrogenase Kinases, Oocyte +8

Quantitative evaluation of fucose reducing effects in a humanized antibody on Fcγ receptor binding and antibody-dependent cell-mediated cytotoxicity activities

Shan Chung, Valerie Quarmby, Xiaoying Gao et al. · mAbs · 2012 · 119 citations · Full text

Detecting low level sequence variants in recombinant monoclonal antibodies

Yi Yang, Alex Strahan, Charlene Li et al. · mAbs · 2010 · 80 citations · Full text

Immunocytochemical Technique, Genetics, Immunology +20

Understanding the intracellular effect of enhanced nutrient feeding toward high titer antibody production process

Marcella Yu, Zhilan Hu, Efren Pacis et al. · Biotechnology and Bioengineering · 2010 · 78 citations

Nutrition, Engineering, Immunology +20

Controlling glycation of recombinant antibody in fed‐batch cell cultures

Inn H. Yuk, Boyan Zhang, Yi Yang et al. · Biotechnology and Bioengineering · 2011 · 76 citations

Glycobiology, Cell Culture, Insulin Signaling +18