Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer

Joseph Tintelnot, Yang Xu, Till Robin Lesker, +28

Nature

TGF-β signaling in Th17 cells promotes IL-22 production and colitis-associated colon cancer

Laura García Pérez, Jan Kempski, Heather M. McGee, +21

Nature Communications

Il-22 ProductionImmunologyGastroenterologyImmune RegulationCell Proliferation +17

IL-10 dampens antitumor immunity and promotes liver metastasis via PD-L1 induction

Ahmad Mustafa Shiri, Tao Zhang, Tanja Bedke, +34

Journal of Hepatology

Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22

Anastasios D. Giannou, Jan Kempski, Ahmad Mustafa Shiri, +72

Immunity

IL22BP Mediates the Antitumor Effects of Lymphotoxin Against Colorectal Tumors in Mice and Humans

Jan Kempski, Anastasios D. Giannou, Kristoffer Riecken, +36

Gastroenterology

Prospective Comparison of the Prognostic Relevance of Circulating Tumor Cells in Blood and Disseminated Tumor Cells in Bone Marrow of a Single Patient's Cohort With Esophageal Cancer

Leonie Konczalla, Tarik Ghadban, Katharina E. Effenberger, +7

Annals of Surgery

Serum Midkine is a clinical significant biomarker for colorectal cancer and associated with poor survival

Marius Kemper, Wiebke Hentschel, Julia‐Kristin Graß, +6

Cancer Medicine

Expansion-enhanced super-resolution radial fluctuations enable nanoscale molecular profiling of pathology specimens

Dominik Kylies, Marina Zimmermann, Fabian Haas, +34

Nature Nanotechnology

Biperiden and mepazine effectively inhibit MALT1 activity and tumor growth in pancreatic cancer

Leonie Konczalla, Daniel Pérez, Nadine Wenzel, +24

International Journal of Cancer

Chemoprevention StrategyPathologyCancer BiologyTumor BiologyPdac Cells +14

Multicytokine-producing CD4+ T cells characterize the livers of patients with NASH

Anna Woestemeier, Pasquale Scognamiglio, Yu Zhao, +28

JCI Insight

T-regulatory CellImmunologyImmune RegulationPathologyFatty Liver Disease +22