Theresa Fletcher

Discovery of Potent, Nonsystemic Apical Sodium-Codependent Bile Acid Transporter Inhibitors (Part 1)

Samuel J. Tremont, Len F. Lee, H. T. Huang et al. · Journal of Medicinal Chemistry · 2005 · 51 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis

Mark E. Schnute, Patrick O’Brien, Joe Nahra et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 50 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Discovery of Potent, Nonsystemic Apical Sodium-Codependent Bile Acid Transporter Inhibitors (Part 2)

H. T. Huang, Samuel J. Tremont, Len F. Lee et al. · Journal of Medicinal Chemistry · 2005 · 48 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Phase I study of azacitidine following donor lymphocyte infusion for relapsed acute myeloid leukemia post allogeneic stem cell transplantation

Armin Ghobadi, Jaebok Choi, Mark A. Fiala et al. · Leukemia Research · 2016 · 37 citations · Full text

Medicine, Hematology, Oncology +12

Discovery of<i>N</i>-(4-Fluoro-3-methoxybenzyl)-6-(2-(((2<i>S</i>,5<i>R</i>)-5-(hydroxymethyl)-1,4-dioxan-2-yl)methyl)-2<i>H</i>-tetrazol-5-yl)-2-methylpyrimidine-4-carboxamide. A Highly Selective and Orally Bioavailable Matrix Metalloproteinase-13 Inhibitor for the Potential Treatment of Osteoarthritis

Peter Ruminski, Mark A. Massa, Joseph W. Strohbach et al. · Journal of Medicinal Chemistry · 2015 · 33 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17