Leandro B. Bernardo

Are the current commercially available oximes capable of reactivating acetylcholinesterase inhibited by the nerve agents of the A-series?

Marcelo C. dos Santos, Fernanda D. Botelho, Arlan da Silva Gonçalves et al. · Archives of Toxicology · 2022 · 28 citations

Life Sciences, Neuroscience, Pharmacology +13

Design, synthesis, <i>in silico</i> studies and <i>in vitro</i> evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators

Daniel A. S. Kitagawa, Rafael B. Rodrigues, Thiago N. Silva et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2021 · 24 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

In Vitro Evaluation of Neutral Aryloximes as Reactivators for Electrophorus eel Acetylcholinesterase Inhibited by Paraoxon

Daniel A. S. Kitagawa, Samir F. de A. Cavalcante, Reuel Lopes de Paula et al. · Biomolecules · 2019 · 18 citations · Full text

Life Sciences, Pharmacology, Toxicology +17

Synthesis and in vitro evaluation of neutral aryloximes as reactivators of Electrophorus eel acetylcholinesterase inhibited by NEMP, a VX surrogate

Samir F. de A. Cavalcante, Daniel A. S. Kitagawa, Rafael B. Rodrigues et al. · Chemico-Biological Interactions · 2019 · 16 citations

Medicine, Medicinal Chemistry, Pharmacology +16

One-Pot Synthesis of NEMP, a VX Surrogate, and Reactivation of NEMP-Inhibited Electrophorus Eel Acetylcholinesterase by Current Antidotes

Samir F. de A. Cavalcante, Daniel A. S. Kitagawa, Rafael Rodrigues et al. · Journal of the Brazilian Chemical Society · 2018 · 11 citations · Full text

Life Sciences, Pharmacology, Toxicology +13