Immune Cell Regulation and Cardiovascular Effects of Sphingosine 1-Phosphate Receptor Agonists in Rodents Are Mediated via Distinct Receptor Subtypes

M J Forrest, S.-Y. Sun, Richard Hajdu, +18

Journal of Pharmacology and Experimental Therapeutics

Neuron-Specific Transduction in the Rat Septohippocampal or Nigrostriatal Pathway by Recombinant Adeno-associated Virus Vectors

Ronald L. Klein, Edwin M. Meyer, Alyson Peel, +4

Experimental Neurology

Neuron-specific TransductionNeurophysiologyNeuroanatomySynaptic TransmissionNigrostriatal Pathway +10

In Vivo RNAi-Mediated α-Synuclein Silencing Induces Nigrostriatal Degeneration

Oleg S. Gorbatyuk, Shoudong Li, Kevin Nash, +8

Molecular Therapy

Neurodegenerative DiseasesAlpha-syn SirnaDegenerative DiseasesControl SirnasImmunology +13

Glucose Regulated Protein 78 Diminishes α-Synuclein Neurotoxicity in a Rat Model of Parkinson Disease

Marina S. Gorbatyuk, Arseniy E. Shabashvili, Weijun Chen, +7

Molecular Therapy

Er Stress MediatorsApoptosisCell DeathDiminishes α-Synuclein NeurotoxicityNeurochemical Biomarkers +23

3-[2,4-Dimethoxybenzylidene]anabaseine (DMXB) selectively activates rat α7 receptors and improves memory-related behaviors in a mecamylamine-sensitive manner

Edwin M. Meyer, Ee Tein Tay, Roger L. Papke, +3

Brain Research

Molecular PharmacologyMecamylamine-sensitive MannerMemory-related BehaviorsSynaptic SignalingRat α7 Receptors +12

NGF gene transfer to intrinsic basal forebrain neurons increases cholinergic cell size and protects from age-related, spatial memory deficits in middle-aged rats

Ronald L. Klein, Aaron C. Hirko, Craig Meyers, +3

Brain Research

Basal Forebrain NeuronsNeurophysiologyNeuroanatomyCholinergic Cell SizeCortical Remodeling +8

Neuroprotective and Memory-Related Actions of Novel Alpha-7 Nicotinic Agents with Different Mixed Agonist/Antagonist Properties

Ee Tein Tay, John A. Zoltewicz, Craig Meyers, +3

Journal of Pharmacology and Experimental Therapeutics

Adeno-associated Viral (AAV) Serotype 5 Vector Mediated Gene Delivery of Endothelin-converting Enzyme Reduces Aβ Deposits in APP + PS1 Transgenic Mice

Nikisha Carty, Kevin Nash, Daniel C. Lee, +6

Molecular Therapy

The loss of glucose-regulated protein 78 (GRP78) during normal aging or from siRNA knockdown augments human alpha-synuclein (α-syn) toxicity to rat nigral neurons

Maxim Salganik, Valeriy Sergeyev, Vishal Shinde, +4

Neurobiology of Aging

Neurodegenerative DiseasesAlzheimer's DiseaseAgingNeurobiology Of DiseaseNigral Neurons +12

Ab-Externo AAV-Mediated Gene Delivery to the Suprachoroidal Space Using a 250 Micron Flexible Microcatheter

Marc C. Peden, Jeff Min, Craig Meyers, +9

PLoS ONE