Mikhail M. Raihstat

Novel derivatives of 1,3,4-oxadiazoles are potent mitostatic agents featuring strong microtubule depolymerizing activity in the sea urchin embryo and cell culture assays

Alex S. Kiselyov, Marina N. Semenova, Natalya B. Chernyshova et al. · European Journal of Medicinal Chemistry · 2010 · 79 citations

Life Sciences, Cell Biology, Pharmacology +17

Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lines

Dmitry V. Demchuk, A. V. Samet, Vladimir I. Ushkarov et al. · Bioorganic & Medicinal Chemistry · 2013 · 77 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9

Synthesis of Antimitotic Polyalkoxyphenyl Derivatives of Combretastatin Using Plant Allylpolyalkoxybenzenes

Victor V. Semenov, Alex S. Kiselyov, Ilia Y. Titov et al. · Journal of Natural Products · 2010 · 72 citations

Natural Sciences, Chemistry, Pharmacology +7

Sea Urchin Embryo Model As a Reliable in Vivo Phenotypic Screen to Characterize Selective Antimitotic Molecules. Comparative evaluation of Combretapyrazoles, -isoxazoles, -1,2,3-triazoles, and -pyrroles as Tubulin-Binding Agents

Marina N. Semenova, Dmitry V. Demchuk, Dmitry V. Tsyganov et al. · ACS Combinatorial Science · 2018 · 65 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Polyalkoxybenzenes from Plants. 5. Parsley Seed Extract in Synthesis of Azapodophyllotoxins Featuring Strong Tubulin Destabilizing Activity in the Sea Urchin Embryo and Cell Culture Assays

Marina N. Semenova, Alex S. Kiselyov, Dmitry V. Tsyganov et al. · Journal of Medicinal Chemistry · 2011 · 62 citations

Medicine, Medicinal Chemistry, Pharmacology +15