Thomas Heinicke

Polyclonal Evolution of Multiple Secondary <i>KIT</i> Mutations in Gastrointestinal Stromal Tumors under Treatment with Imatinib Mesylate

Eva Wardelmann, Sabine Merkelbach‐Bruse, Katharina Pauls et al. · Clinical Cancer Research · 2006 · 365 citations

Medicine, Molecular Biology, Oncology +16

High activity of sorafenib in FLT3-ITD-positive acute myeloid leukemia synergizes with allo-immune effects to induce sustained responses

Stephan Metzelder, Thomas Schroeder, Anemone Finck et al. · Leukemia · 2012 · 225 citations

Medicine, Immunology, Oncology +15

Deletion of Trp‐557 and Lys‐558 in the juxtamembrane domain of the <i>c‐kit</i> protooncogene is associated with metastatic behavior of gastrointestinal stromal tumors

Eva Wardelmann, Inge Losen, Volkmar Hans et al. · International Journal of Cancer · 2003 · 220 citations · Full text

Medicine, Genetics, Oncology +17

Acquired resistance to imatinib in gastrointestinal stromal tumours caused by multiple KIT mutations

Eva Wardelmann, Nadja Thomas, Sabine Merkelbach‐Bruse et al. · The Lancet Oncology · 2005 · 191 citations

Medicine, Genetics, Oncology +14

Novel Germline Mutation of KIT Associated With Familial Gastrointestinal Stromal Tumors and Mastocytosis

Karin Hartmann, Eva Wardelmann, Yongsheng Ma et al. · Gastroenterology · 2005 · 189 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16