Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome

Yongyong Shi, Han Zhao, Yuhua Shi, +50

Nature Genetics

Genome-wide Association StudyGeneticsPolygenic RiskGenetic EpidemiologyPolycystic Ovary Syndrome +6

Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia

Zhiqiang Li, Jianhua Chen, Hao Yu, +35

Nature Genetics

Genome-wide Association StudyPsychiatryGeneticsPsychiatric GeneticsGenetic Epidemiology +5

BMP restricts stemness of intestinal Lgr5+ stem cells by directly suppressing their signature genes

Zhen Qi, Yehua Li, Bing Zhao, +10

Nature Communications

p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling

Xueying Wang, Hui-Yi Kua, Yuanyu Hu, +8

The Journal of Cell Biology

Common variants on 8p12 and 1q24.2 confer risk of schizophrenia

Yongyong Shi, Zhiqiang Li, Qi Xu, +37

Nature Genetics

PsychiatryGenetic DisorderGeneticsPsychiatric GeneticsGenetic Epidemiology +5

Activation of p38 Mitogen-Activated Protein Kinase Is Required for Osteoblast Differentiation

Yuanyu Hu, Emily Chan, Sherry X. Wang, +1

Endocrinology

SclerostinCell DeathP38 MapkCellular PhysiologyOsteoporosis +15

Gut stem cell aging is driven by mTORC1 via a p38 MAPK-p53 pathway

Dan He, Hongguang Wu, Jinnan Xiang, +11

Nature Communications

FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging

Hanjun Li, Pei Liu, Shuqin Xu, +12

Journal of Clinical Investigation

Bone Marrow MscsMsc SenescenceAgingAdult Stem CellCell Death +22

Mice deficient in Abl are osteoporotic and have defects in osteoblast maturation

Baojie Li, Sharon Boast, Kenia de los Santos, +5

Nature Genetics

Osteoblast MaturationBone Morphogenic ProteinBone RepairBone MetabolismMice Deficient +5

Deletion of DDB1 in Mouse Brain and Lens Leads to p53-Dependent Elimination of Proliferating Cells

Yong Cang, Jianxuan Zhang, Sally A. Nicholas, +4

Cell

MitophagyCell RegulationCell DivisionApoptosisCell Death +10