Yanhong Gu

Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer

Wenjie Guo, Yang Sun, Wen Liu et al. · Autophagy · 2014 · 307 citations · Full text

Life Sciences, Immunology, Oncology +17

Inhibition of AIM2 inflammasome-mediated pyroptosis by Andrographolide contributes to amelioration of radiation-induced lung inflammation and fibrosis

Jian Gao, Shuang Peng, Xinni Shan et al. · Cell Death and Disease · 2019 · 191 citations · Full text

Medicine, Immunology, Pharmacology +17

Camrelizumab plus gemcitabine and oxaliplatin (GEMOX) in patients with advanced biliary tract cancer: a single-arm, open-label, phase II trial

Xiaofeng Chen, Xiaofeng Wu, Hao Wu et al. · Journal for ImmunoTherapy of Cancer · 2020 · 160 citations · Full text

Medicine, Oncology, Pharmacology +17

Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis

Wenjie Guo, Wen Liu, Zhen Chen et al. · Nature Communications · 2017 · 145 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

A novel benzo[d]imidazole derivate prevents the development of dextran sulfate sodium-induced murine experimental colitis via inhibition of NLRP3 inflammasome

Wen Liu, Wenjie Guo, Jing Wu et al. · Biochemical Pharmacology · 2013 · 141 citations

Life Sciences, Immunology, Pharmacology +12