Cheng Chen

Optimization of 4-1BB antibody for cancer immunotherapy by balancing agonistic strength with FcγR affinity

Xinyue Qi, Fanlin Li, Yi Wu et al. · Nature Communications · 2019 · 133 citations · Full text

Pharmacy, Immunology, Oncology +17

The kinase complex mTORC2 promotes the longevity of virus-specific memory CD4+ T cells by preventing ferroptosis

Yifei Wang, Tian Qin, Yaxing Hao et al. · Nature Immunology · 2021 · 102 citations

Life Sciences, Immunology, Molecular Biology +12

Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors

Ming Xu, Changhong Zhu, Xian Zhao et al. · Oncotarget · 2014 · 85 citations · Full text

Medicine, Molecular Biology, Oncology +17

IL-22 secreting CD4 + T cells in the patients with neuromyelitis optica and multiple sclerosis

Wen Xu, Rui Li, Yongqiang Dai et al. · Journal of Neuroimmunology · 2013 · 80 citations

Life Sciences, Immunology, Neurology +14

Self‐Reinforced Bimetallic Mito‐Jammer for Ca ²⁺ Overload‐Mediated Cascade Mitochondrial Damage for Cancer Cuproptosis Sensitization

Chier Du, Xun Guo, Xiaoling Qiu et al. · Advanced Science · 2024 · 69 citations · Full text

Medicine, Oncology, Pharmacology +15