Loes I. van Eijk

Design of Nonpeptidic Topomimetics of Antiangiogenic Proteins With Antitumor Activities

Ruud P.M. Dings, Xuemei Chen, Debby M.E.I. Hellebrekers et al. · JNCI Journal of the National Cancer Institute · 2006 · 111 citations · Full text

The designer antiangiogenic peptide anginex targets tumor endothelial cells and inhibits tumor growth in animal models

Daisy W.J. van der Schaft, Ruud P.M. Dings, Quido G. de Lussanet et al. · The FASEB Journal · 2002 · 103 citations

Endothelial Cells, Immunology, Inhibits Tumor Growth +18

Platelet Factor 4 and Interleukin-8 CXC Chemokine Heterodimer Formation Modulates Function at the Quaternary Structural Level

Irina V. Nesmelova, Yuk Y. Sham, Arkadiusz Z. Dudek et al. · Journal of Biological Chemistry · 2004 · 93 citations · Full text

Chemokine Biology, Nmr Spectroscopy, Immunology +21

Design of a Partial Peptide Mimetic of Anginex with Antiangiogenic and Anticancer Activity

Kevin H. Mayo, Ruud P.M. Dings, Carolee Flader et al. · Journal of Biological Chemistry · 2003 · 72 citations · Full text

Parent Anginex, Peptide Engineering, Partial Peptide Mimetic +23

beta-Sheet is the bioactive conformation of the anti-angiogenic anginex peptide

Ruud P.M. Dings, M. Arroyo, Nathan A. Lockwood et al. · Biochemical Journal · 2003 · 54 citations · Full text

Bioactive Conformation, Medicinal Chemistry, Disulphide Bonds +13