A Novel Approach for Predicting P-Glycoprotein (ABCB1) Inhibition Using Molecular Interaction Fields

Fabio Broccatelli, Emanuele Carosati, Annalisa Neri, +4

Journal of Medicinal Chemistry

Medicinal ChemistryHigh AccuracyDrug TargetBiochemistryPgp Inhibition +12

Potentiation of mitochondrial Ca2+ sequestration by taurine

Mitri Palmi, Gisèle Tchuisseu Youmbi, Fabio Fusi, +4

Biochemical Pharmacology

Mitochondrial FunctionPhysiologyMitochondrial Ca2+ SequestrationMetabolismMedicine +2

Synthesis and Biological Evaluation of Amidine, Guanidine, and Thiourea Derivatives of 2-Amino(6-trifluoromethoxy)benzothiazole as Neuroprotective Agents Potentially Useful in Brain Diseases

Maurizio Anzini, Alessia Chelini, Alessandra Mancini, +9

Journal of Medicinal Chemistry

Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 4. Identification of New Potent and Selective Ligands for the Cannabinoid Type 2 Receptor with Diverse Substitution Patterns and Antihyperalgesic Effects in Mice

Serena Pasquini, Maria De Rosa, Valentina Pedani, +10

Journal of Medicinal Chemistry

Molecular Pain4-Quinolone-3-carboxylic Acid MotifPharmacotherapyExperimental PharmacologyMedicinal Chemistry +16

Calcium Channel Antagonists Discovered by a Multidisciplinary Approach

Emanuele Carosati, Gabriele Cruciani, Alberto Chiarini, +12

Journal of Medicinal Chemistry

Interactions of taurine and structurally related analogues with the GABAergic system and taurine binding sites of rabbit brain

Maria Frosini, Casilde Sesti, Stefania Dragoni, +5

British Journal of Pharmacology

Thymus vulgaris L. Essential Oil Solid Formulation: Chemical Profile and Spasmolytic and Antimicrobial Effects

Matteo Micucci, Michele Protti, Rita Aldini, +8

Biomolecules

Interactions of human P-glycoprotein transport substrates and inhibitors at the drug binding domain: Functional and molecular docking analyses

Onat Kadioglu, Mohamed E.M. Saeed, Massimo Valoti, +3

Biochemical Pharmacology

Drug TargetBiochemistryG Protein-coupled ReceptorMedicineGlycobiology +4

A specific taurine recognition site in the rabbit brain is responsible for taurine effects on thermoregulation

Maria Frosini, Casilde Sesti, Simona Saponara, +5

British Journal of Pharmacology

Rectal temperature and prostaglandin E 2 increase in cerebrospinal fluid of conscious rabbits after intracerebroventricular injection of hemoglobin

Maria Frosini, Casilde Sesti, Massimo Valoti, +4

Experimental Brain Research

Animal PhysiologyCerebral Vascular RegulationRectal TemperatureNeurophysiologyMedicine +10