A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells

B Bernstein, Tarjei S. Mikkelsen, Xiaohui Xie, +12

Cell

ChromatinDevelopmental BiologyChromatin StructureChromatin RemodelingMedicine +11

Expanded encyclopaedias of DNA elements in the human and mouse genomes

Federico Abascal, Reyes Acosta, Nicholas J. Addleman, +530

Nature

Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters

Andrea Ventura, Amanda Young, Monte M. Winslow, +10

Cell

Mir-17∼92 FamilyFunctional GenomicsGeneticsRna BiologyMirna Clusters +8

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

Philip L. De Jager, Gyan Srivastava, Katie Lunnon, +26

Nature Neuroscience

Alzheimer's DiseaseEpigenetic ChangeGeneticsDementiaOther Loci +10

Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses

Ido Amit, Manuel Garber, Nicolas Chevrier, +22

Science

EngineeringGeneticsImmunologyTranscriptomics TechnologyNetwork Model +18

Reprogramming Efficiency Following Somatic Cell Nuclear Transfer Is Influenced by the Differentiation and Methylation State of the Donor Nucleus

Robert Blelloch, Zhongde Wang, Alex Meissner, +3

Stem Cells

Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing

Heinz Linhart, Haijiang Lin, Yasuhiro Yamada, +9

Genes & Development

Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission

Ralda Nehme, Emanuela Zuccaro, Sulagna Ghosh, +18

Cell Reports

:Gfp Reporter GeneDevelopmental Cognitive NeuroscienceSynaptic TransmissionNeurotransmitterNmdar-mediated Synaptic Transmission +18

Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis

Yasuhiro Yamada, Laurie Jackson‐Grusby, Heinz Linhart, +4

Proceedings of the National Academy of Sciences

Perspectives on ENCODE

Federico Abascal, Reyes Acosta, Nicholas J. Addleman, +514

Nature