Lynda K. Hawkins

Novel immunocompetent murine tumor models for the assessment of replication-competent oncolytic adenovirus efficacy

Gunnel Halldén, Richard Hill, Yaohe Wang et al. · Molecular Therapy · 2003 · 113 citations

Life Sciences, Immunology, Oncology +17

An oncolytic adenovirus selective for retinoblastoma tumor suppressor protein pathway-defective tumors: dependence on E1A, the E2F-1 promoter, and viral replication for selectivity and efficacy.

John Jakubczak, Patricia C. Ryan, M Gorziglia et al. · PubMed · 2003 · 99 citations

Life Sciences, Molecular Biology, Oncology +17

Developing Novel Oncolytic Adenoviruses through Bioselection

Wen Yan, Galila Kitzes, Farid Dormishian et al. · Journal of Virology · 2003 · 54 citations · Full text

Medicine, Molecular Biology, Oncology +14

Antitumor efficacy and tumor-selective replication with a single intravenous injection of OAS403, an oncolytic adenovirus dependent on two prevalent alterations in human cancer

Patricia C. Ryan, John Jakubczak, David A. Stewart et al. · Cancer Gene Therapy · 2004 · 40 citations

Medicine, Cancer Biology, Oncology +14

Systemic Gene-Directed Enzyme Prodrug Therapy of Hepatocellular Carcinoma Using a Targeted Adenovirus Armed with Carboxypeptidase G2

Silke Schepelmann, Paul L. Hallenbeck, Lesley Ogilvie et al. · Cancer Research · 2005 · 32 citations

Pharmacy, Molecular Medicine, Oncology +17