Patrick Urban

Ceritinib versus chemotherapy in patients with ALK-rearranged non-small-cell lung cancer previously given chemotherapy and crizotinib (ASCEND-5): a randomised, controlled, open-label, phase 3 trial

Alice T. Shaw, Tae Min Kim, Lucio Crinò et al. · The Lancet Oncology · 2017 · 574 citations · Full text

Medicine, Ceritinib Versus Chemotherapy, Pathology +6

Buparlisib plus fulvestrant versus placebo plus fulvestrant in postmenopausal, hormone receptor-positive, HER2-negative, advanced breast cancer (BELLE-2): a randomised, double-blind, placebo-controlled, phase 3 trial

José Baselga, Seock‐Ah Im, Hiroji Iwata et al. · The Lancet Oncology · 2017 · 532 citations · Full text

Advanced Breast Cancer, Breast Oncology, Oncology +13

A randomized adaptive phase II/III study of buparlisib, a pan-class I PI3K inhibitor, combined with paclitaxel for the treatment of HER2– advanced breast cancer (BELLE-4)

Miguel Martín, A. Chan, Luc Dirix et al. · Annals of Oncology · 2016 · 178 citations · Full text

Breast Oncology, Medicine, Pharmacology +6

Neoadjuvant buparlisib plus trastuzumab and paclitaxel for women with HER2+ primary breast cancer: A randomised, double-blind, placebo-controlled phase II trial (NeoPHOEBE)

Sibylle Loibl, Lorena de la Peña, Valentina Nekljudova et al. · European Journal of Cancer · 2017 · 100 citations · Full text

Breast Oncology, Medicine, Clinical Trials +6

Abstract S6-01: <i>PIK3CA</i> status in circulating tumor DNA (ctDNA) predicts efficacy of buparlisib (BUP) plus fulvestrant (FULV) in postmenopausal women with endocrine-resistant HR+/HER2– advanced breast cancer (BC): First results from the randomized, phase III BELLE-2 trial

J. Baselga, S-A. Im, Hiroji Iwata et al. · Cancer Research · 2016 · 88 citations

Tumor Biology, Endocrine Oncology, Breast Oncology +15