Donald J. Graham

In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors

Jon H. Condra, William A. Schleif, O M Blahy et al. · Nature · 1995 · 978 citations

Protease Inhibitors, Human Retrovirus, Immunology +10

Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor

Jon H. Condra, Daniel Holder, William A. Schleif et al. · Journal of Virology · 1996 · 405 citations · Full text

Immunology, Vivo Viral Resistance, Molecular Biology +17

MK-5172, a Selective Inhibitor of Hepatitis C Virus NS3/4a Protease with Broad Activity across Genotypes and Resistant Variants

Vincenzo Summa, Steven W. Ludmerer, John A. McCauley et al. · Antimicrobial Agents and Chemotherapy · 2012 · 254 citations · Full text

Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor

Steven J. Harper, John A. McCauley, Michael T. Rudd et al. · ACS Medicinal Chemistry Letters · 2012 · 201 citations · Full text

Immunology, Molecular Biology, Pharmacotherapy +19

Discovery of MK‐8742: An HCV NS5A Inhibitor with Broad Genotype Activity

Craig A. Coburn, Peter T. Meinke, Wei Chang et al. · ChemMedChem · 2013 · 196 citations · Full text

Hcv Ns5a Inhibitor, Broad Genotype Activity, Vitro Potency Profiles +17