Fangyi Zhu

Chemical genetics of Plasmodium falciparum

W. Armand Guiguemde, Anang A. Shelat, David C. Bouck et al. · Nature · 2010 · 565 citations · Full text

Biology, Biochemical Taxonomy, Genetics +7

(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of <i>Plasmodium</i>

Marı́a Belén Jiménez-Dı́az, Daniel Ebert, Yandira G. Salinas et al. · Proceedings of the National Academy of Sciences · 2014 · 238 citations · Full text

Phenotypic Screening, Antiparasitic Agent, Malaria +17

Identification and Characterization of the First Small Molecule Inhibitor of MDMX

Damon R. Reed, Ying Shen, Anang A. Shelat et al. · Journal of Biological Chemistry · 2010 · 193 citations · Full text

Small Molecule Inhibitors, Drug Target, Chemoprevention Strategy +19

Targeting the p53 Pathway in Retinoblastoma with Subconjunctival Nutlin-3a

Rachel C. Brennan, Sara M. Federico, Cori Bradley et al. · Cancer Research · 2011 · 93 citations · Full text

Ocular Disease, Oncology, Cell Regulation +12

Lead Optimization of 3-Carboxyl-4(1<i>H</i>)-Quinolones to Deliver Orally Bioavailable Antimalarials

Yiqun Zhang, Julie Clark, Michele Connelly et al. · Journal of Medicinal Chemistry · 2012 · 78 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Bioorganic Chemistry +13