J. Ned Pruitt

Mutation of the acetylcholine receptor α subunit causes a slow-channel myasthenic syndrome by enhancing agonist binding affinity

Steven M. Sine, Kinji Ohno, Cecilia Bouzat et al. · Neuron · 1995 · 267 citations · Full text

Life Sciences, Biochemistry, Neuroscience +13

Congenital Myasthenic Syndrome Caused by Decreased Agonist Binding Affinity Due to a Mutation in the Acetylcholine Receptor ε Subunit

Kinji Ohno, Hai-Long Wang, Margherita Milone et al. · Neuron · 1996 · 228 citations · Full text

Life Sciences, Genetics, Pharmacology +15

Long-term effect of thymectomy plus prednisone versus prednisone alone in patients with non-thymomatous myasthenia gravis: 2-year extension of the MGTX randomised trial

Gil I. Wolfe, Henry J. Kaminski, Inmaculada Aban et al. · The Lancet Neurology · 2019 · 223 citations · Full text

Medicine, Endocrinology, Surgery +5

Congenital Myasthenic Syndromes due to Heteroallelic Nonsense/Missense Mutations in the Acetylcholine Receptor   Subunit Gene: Identification and Functional Characterization of Six New Mutations

Kinji Ohno, Polly A. Quiram, Margherita Milone et al. · Human Molecular Genetics · 1997 · 157 citations · Full text

Life Sciences, Genetics, Neuroscience +13

Slow-channel myasthenic syndrome caused by enhanced activation, desensitization, and agonist binding affinity attributable to mutation in the M2 domain of the acetylcholine receptor alpha subunit.

Margherita Milone, Hai Long Wang, Kinji Ohno et al. · PubMed · 1997 · 134 citations

Life Sciences, Genetics, Neurology +17