Feiyu Fred Zhang

LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2

Hannah Nguyen, Abdellah Allali‐Hassani, Stephen Antonysamy et al. · Journal of Biological Chemistry · 2015 · 131 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +11

Structural Bases of PAS Domain-regulated Kinase (PASK) Activation in the Absence of Activation Loop Phosphorylation

Chintan K. Kikani, Stephen A. Antonysamy, J.B. Bonanno et al. · Journal of Biological Chemistry · 2010 · 36 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Discovery and clinical translation of ceperognastat, an O‐GlcNAcase (OGA) inhibitor, for the treatment of Alzheimer's disease

William Kielbasa, Paul Goldsmith, Kevin B. Donnelly et al. · Alzheimer s & Dementia Translational Research & Clinical Interventions · 2024 · 21 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Abstract P142: Preclinical characterization of LOX-22783, a highly potent, mutant-selective and brain-penetrant allosteric PI3Kα H1047R inhibitor

Anke Klippel, Rui Wang, Loredana Puca et al. · Molecular Cancer Therapeutics · 2021 · 11 citations

Medicine, Oncology, Pharmacology +17