Ian Fraser

Blockade of Orexin-1 Receptors Attenuates Orexin-2 Receptor Antagonism-Induced Sleep Promotion in the Rat

Christine Dugovic, Jonathan Shelton, Leah Aluisio et al. · Journal of Pharmacology and Experimental Therapeutics · 2009 · 230 citations

Life Sciences, Neuroscience, Pharmacology +16

Pharmacological characterization of a novel centrally permeable <scp>P2X7</scp> receptor antagonist: <scp>JNJ</scp>‐47965567

Anindya Bhattacharya, Qi Wang, Hong Ao et al. · British Journal of Pharmacology · 2013 · 198 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement

James R. Shoblock, Natalie Welty, Leah Aluisio et al. · Psychopharmacology · 2010 · 159 citations

Life Sciences, Neuroscience, Pharmacology +15

Translational Evaluation of JNJ-18038683, a 5-Hydroxytryptamine Type 7 Receptor Antagonist, on Rapid Eye Movement Sleep and in Major Depressive Disorder

Pascal Bonaventure, Christine Dugovic, Michelle Kramer et al. · Journal of Pharmacology and Experimental Therapeutics · 2012 · 86 citations

Medicine, Pharmacology, Psychiatry +16

Characterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia

Pascal Bonaventure, Jonathan Shelton, Sujin Yun et al. · Journal of Pharmacology and Experimental Therapeutics · 2015 · 82 citations

Medicine, Neuroscience, Pharmacology +14