Samuel Hsiao

A phase 2, randomized, double‐blind, placebo‐controlled study to evaluate the efficacy and safety of soticlestat as adjunctive therapy in pediatric patients with Dravet syndrome or Lennox–Gastaut syndrome (<scp>ELEKTRA</scp>)

Cecil D. Hahn, Yuwu Jiang, Vicente Villanueva et al. · Epilepsia · 2022 · 76 citations · Full text

Medicine, Pediatrics, Pharmacology +17

Efficacy, safety, and tolerability of soticlestat as adjunctive therapy for the treatment of seizures in patients with Dup15q syndrome or CDKL5 deficiency disorder in an open-label signal-finding phase II study (ARCADE)

Scott Demarest, Shafali Jeste, Nitin Agarwal et al. · Epilepsy & Behavior · 2023 · 20 citations · Full text

Medicine, Neurology, Pharmacology +6

Investigation of the absolute bioavailability, mass balance, metabolism, and excretion of the cholesterol 24‐hydroxylase inhibitor soticlestat in healthy volunteers

Wei Yin, T. Eric Ballard, Xiaochun Zhu et al. · British Journal of Clinical Pharmacology · 2023 · 11 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17