Bernard C. H. Lee

A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening

Helen H.N. Yan, Hoi Cheong Siu, Simon Law et al. · Cell stem cell · 2018 · 723 citations · Full text

Medicine, Cancer Biology, Oncology +12

RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutation

Helen H.N. Yan, Jeffrey C W Lai, Siu Lun Ho et al. · Gut · 2016 · 203 citations

Medicine, Genetics, Oncology +17

Increased somatic mutation burdens in normal human cells due to defective DNA polymerases

Philip S. Robinson, Tim Coorens, Claire Palles et al. · Nature Genetics · 2021 · 176 citations · Full text

Medicine, Genetics, Molecular Genetics +15

Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles

Helen H.N. Yan, Hoi Cheong Siu, Siu Lun Ho et al. · Gut · 2020 · 138 citations · Full text

Medicine, Molecular Genetics, Oncology +17

Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells

Philip S. Robinson, Laura E. Thomas, Federico Abascal et al. · Nature Communications · 2022 · 61 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17