Valentine M. Macaulay

Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease.

Giles Hellawell, Gareth D. H. Turner, David Davies et al. · PubMed · 2002 · 376 citations

Medicine, Molecular Biology, Oncology +17

Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation

Sophia X. Pfister, Enni Markkanen, Yanyan Jiang et al. · Cancer Cell · 2015 · 309 citations · Full text

Medicine, Cancer Biology, Oncology +12

Aberrant succination of proteins in fumarate hydratase‐deficient mice and HLRCC patients is a robust biomarker of mutation status

Chiara Bardella, Mona El‐Bahrawy, Norma Frizzell et al. · The Journal of Pathology · 2011 · 279 citations

Medicine, Biochemistry, Oncology +17

Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of β-catenin

Martin P. Playford, David Bicknell, Walter F. Bodmer et al. · Proceedings of the National Academy of Sciences · 2000 · 279 citations

Life Sciences, Cell Biology, Molecular Biology +16

The Efficacy of Small Interfering RNAs Targeted to the Type 1 Insulin-like Growth Factor Receptor (IGF1R) Is Influenced by Secondary Structure in the IGF1R Transcript

Erin A. Bohula, A. J. Salisbury, Muhammad Sohail et al. · Journal of Biological Chemistry · 2003 · 235 citations · Full text

Life Sciences, Molecular Biology, Oncology +12