Ed Keystone

Radiographic changes in rheumatoid arthritis patients attaining different disease activity states with methotrexate monotherapy and infliximab plus methotrexate: the impacts of remission and tumour necrosis factor blockade

Josef S Smolen, C. Han, Désirée van der Heijde et al. · Annals of the Rheumatic Diseases · 2008 · 237 citations

Medicine, Clinical Sciences, Pharmacotherapy +13

Association of the lymphoid tyrosine phosphatase R620W variant with rheumatoid arthritis, but not Crohn's disease, in Canadian populations

Mark Van Oene, Richard F. Wintle, Xiangdong Liu et al. · Arthritis & Rheumatism · 2005 · 132 citations

Life Sciences, Genetics, Molecular Genetics +12

Combination leflunomide and methotrexate (MTX) therapy for patients with active rheumatoid arthritis failing MTX monotherapy: open-label extension of a randomized, double-blind, placebo controlled trial.

Joel M. Kremer, Mark C. Genovese, Grant W. Cannon et al. · PubMed · 2004 · 92 citations

Medicine, Clinical Sciences, Pharmacotherapy +13

The influence of age at disease onset on disease activity and disability: results from the Ontario Best Practices Research Initiative

Thanu Nadarajah Ruban, Binu Jacob, Janet Pope et al. · Clinical Rheumatology · 2015 · 45 citations

Medicine, Geriatric Medicine, Preventive Medicine +14

Self-reported comorbidity is common in early inflammatory arthritis and associated with poorer function and worse arthritis disease outcomes: results from the Canadian Early Arthritis Cohort

Carol Hitchon, Gilles Boire, Boulos Haraoui et al. · Lara D. Veeken · 2016 · 38 citations · Full text

Medicine, Clinical Sciences, Internal Medicine +17