Subramaniam Krishnananthan

Discovery of a 1<i>H</i>-Benzoimidazol-2-yl)-1<i>H</i>-pyridin-2-one (BMS-536924) Inhibitor of Insulin-like Growth Factor I Receptor Kinase with in Vivo Antitumor Activity

Mark D. Wittman, Joan M. Carboni, Ricardo M. Attar et al. · Journal of Medicinal Chemistry · 2005 · 135 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Discovery of Milvexian, a High-Affinity, Orally Bioavailable Inhibitor of Factor XIa in Clinical Studies for Antithrombotic Therapy

Andrew K. Dilger, Kumar B. Pabbisetty, James R. Corte et al. · Journal of Medicinal Chemistry · 2021 · 97 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Discovery of an Oxycyclohexyl Acid Lysophosphatidic Acid Receptor 1 (LPA₁) Antagonist BMS-986278 for the Treatment of Pulmonary Fibrotic Diseases

Peter T. W. Cheng, Robert F. Kaltenbach, Hao Zhang et al. · Journal of Medicinal Chemistry · 2021 · 57 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

A Strategy to Minimize Reactive Metabolite Formation: Discovery of (<i>S</i>)-4-(1-Cyclopropyl-2-methoxyethyl)-6-[6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino]-5-oxo-4,5-dihydropyrazine-2-carbonitrile as a Potent, Orally Bioavailable Corticotropin-Releasing Factor-1 Receptor Antagonist

Richard A. Hartz, Vijay T. Ahuja, Xiaoliang Zhuo et al. · Journal of Medicinal Chemistry · 2009 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

(+)-Dinapsoline:  An Efficient Synthesis and Pharmacological Profile of a Novel Dopamine Agonist

Sing‐Yuen Sit, Kai Xie, Swanee Jacutin-Porte et al. · Journal of Medicinal Chemistry · 2002 · 42 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13