Jake A. Kloeber

Metabolic regulation of homologous recombination repair by MRE11 lactylation

Yuping Chen, Jinhuan Wu, Linhui Zhai et al. · Cell · 2023 · 404 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Homologous recombination into the eosinophil peroxidase locus generates a strain of mice expressing <i>Cre</i> recombinase exclusively in eosinophils

Alfred D. Doyle, Elizabeth A. Jacobsen, Sergei I. Ochkur et al. · Journal of Leukocyte Biology · 2013 · 109 citations · Full text

Life Sciences, Genetics, Immunology +14

Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL

Praveen Anand, Amy Guillaumet-Adkins, Valeriya Dimitrova et al. · Blood · 2020 · 97 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +12

Eosinophil-derived IL-13 promotes emphysema

Alfred D. Doyle, Manali Mukherjee, William E. LeSuer et al. · European Respiratory Journal · 2019 · 85 citations · Full text

Veterinary Medicine, Immunology, Pathology +17

MET Amplification Attenuates Lung Tumor Response to Immunotherapy by Inhibiting STING

Yong Zhang, Qifan Yang, Xiangyu Zeng et al. · Cancer Discovery · 2021 · 81 citations · Full text

Life Sciences, Immunology, Oncology +17