Chen-Hsun Hsu

MLN4924, a novel protein neddylation inhibitor, suppresses proliferation and migration of human urothelial carcinoma: In vitro and in vivo studies

Kuan-Lin Kuo, I-Lin Ho, Chung‐Sheng Shi et al. · Cancer Letters · 2015 · 61 citations

Urology, Vivo Studies, Genitourinary Cancer +6

MLN4924 Synergistically Enhances Cisplatin-induced Cytotoxicity via JNK and Bcl-xL Pathways in Human Urothelial Carcinoma

I-Lin Ho, Kuan-Lin Kuo, Shing‐Hwa Liu et al. · Scientific Reports · 2015 · 44 citations · Full text

The Deubiquitinating Enzyme Inhibitor PR-619 Enhances the Cytotoxicity of Cisplatin via the Suppression of Anti-Apoptotic Bcl-2 Protein: In Vitro and In Vivo Study

Kuan-Lin Kuo, Shing‐Hwa Liu, Wei‐Chou Lin et al. · Cells · 2019 · 27 citations · Full text

Bladder Uc Treatment, Chemoprevention Strategy, Apoptosis +16

Neddylation inhibitor, MLN4924 suppresses angiogenesis in huvecs and solid cancers: <i>in vitro</i> and <i>in vivo</i> study.

Chung‐Sheng Shi, Kuan-Lin Kuo, Wei‐Chou Lin et al. · PubMed · 2020 · 26 citations · Full text

PR-619, a General Inhibitor of Deubiquitylating Enzymes, Diminishes Cisplatin Resistance in Urothelial Carcinoma Cells through the Suppression of c-Myc: An In Vitro and In Vivo Study

Fu-Shun Hsu, Wei‐Chou Lin, Kuan-Lin Kuo et al. · International Journal of Molecular Sciences · 2021 · 25 citations · Full text

C-myc Expression, Cancer Biology, Tumor Biology +17