Hugh Mackie

The Oxidative DNA Lesion 8,5′-(S)-Cyclo-2′-deoxyadenosine Is Repaired by the Nucleotide Excision Repair Pathway and Blocks Gene Expression in Mammalian Cells

Philip J. Brooks, Dean S. Wise, David A. Berry et al. · Journal of Biological Chemistry · 2000 · 299 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Pyrrolo-dC and pyrrolo-C: fluorescent analogs of cytidine and 2′-deoxycytidine for the study of oligonucleotides

David A. Berry, K. W. Jung, Dean S. Wise et al. · Tetrahedron Letters · 2004 · 139 citations

Life Sciences, Biochemistry, Molecular Biology +12

Therapeutic glucocorticoids prevent bone loss but drive muscle wasting when administered in chronic polyarthritis

Chloe Fenton, J. Matthew Webster, Claire Martin et al. · Arthritis Research & Therapy · 2019 · 31 citations · Full text

Medicine, Immunology, Pathobiology +17

Improved Synthesis of Trinucleotide Phosphoramidites and Generation of Randomized Oligonucleotide Libraries

Andrey Yagodkin, Alex Azhayev, Jarkko Roivainen et al. · Nucleosides Nucleotides & Nucleic Acids · 2007 · 29 citations

Pharmacy, Biochemistry, Biotechnology +12

Combination of DMT-mononucleotide and Fmoc-trinucleotide phosphoramidites in oligonucleotide synthesis affords an automatable codon-level mutagenesis method

Paul Gaytán, Jorge Yáñez, Filiberto Sánchez et al. · Chemistry & Biology · 1998 · 28 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +13