Po‐wai Yuen

Non-erythroid α-spectrin breakdown by calpain and interleukin 1 β-converting-enzyme-like protease(s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosis

Rathna Nath, Kadee J. Raser, Daniel Stafford et al. · Biochemical Journal · 1996 · 426 citations · Full text

Kda Sbdp, Apoptosis, Immunology +23

An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective.

Kevin Wang, Rathna Nath, Avigail Posner et al. · Proceedings of the National Academy of Sciences · 1996 · 274 citations · Full text

Inhibitory Activity, Medicinal Chemistry, Protein Function +14

Crystal structure of calcium bound domain VI of calpain at 1.9 Å resolution and its role in enzyme assembly, regulation, and inhibitor binding

G. Lin, Debasish Chattopadhyay, Masatoshi Maki et al. · Nature Structural Biology · 1997 · 190 citations

Crystal Structure, Enzyme Assembly, Protein Assembly +9

The Novel Calpain Inhibitor SJA6017 Improves Functional Outcome after Delayed Administration in a Mouse Model of Diffuse Brain Injury

Nancy C. Kupina, Rathna Nath, Eric Bernath et al. · Journal of Neurotrauma · 2001 · 112 citations · Full text

Functional Outcome, Delayed Administration, Social Sciences +23

Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design

Matthew Volgraf, Benjamin D. Sellers, Yu Jiang et al. · Journal of Medicinal Chemistry · 2016 · 102 citations · Full text

Synaptic Transmission, Neurotransmitter, Synaptic Signaling +28