Lynn McGarry

Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress

Zachary T. Schug, Barrie Peck, Dylan T. Jones et al. · Cancer Cell · 2015 · 820 citations · Full text

Medicine, Cancer Biology, Oncology +16

Predicting Cancer-Specific Vulnerability via Data-Driven Detection of Synthetic Lethality

Livnat Jerby‐Arnon, Nadja Pfetzer, Yedael Y. Waldman et al. · Cell · 2014 · 306 citations · Full text

Life Sciences, Bioinformatics, Oncology +16

Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy

Bryan W. Miller, Jennifer P. Morton, Mark Pinese et al. · EMBO Molecular Medicine · 2015 · 266 citations · Full text

Medicine, Oncology, Pharmacology +17

Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments

Barrie Peck, Zachary T. Schug, Beatrice Dankworth et al. · Cancer & Metabolism · 2016 · 262 citations · Full text

Life Sciences, Biochemistry, Oncology +17

NOTUM from Apc-mutant cells biases clonal competition to initiate cancer

Dustin J. Flanagan, Nalle Pentinmikko, Kalle Luopajärvi et al. · Nature · 2021 · 252 citations · Full text

Medicine, Cancer Biology, Oncology +12