Helene L. Pedersen

Carbonic anhydrases reduce the acidity of the tumor microenvironment, promote immune infiltration, decelerate tumor growth, and improve survival in ErbB2/HER2-enriched breast cancer

Soojung Lee, Nicolai J. Toft, Trine V. Axelsen et al. · Breast Cancer Research · 2023 · 39 citations · Full text

Life Sciences, Biochemistry, Oncology +17

Antibodies toward Na+,HCO3–-cotransporter NBCn1/SLC4A7 block net acid extrusion and cause pH-dependent growth inhibition and apoptosis in breast cancer

Trine V. Axelsen, Claus Olesen, Danish Khan et al. · British Journal of Cancer · 2024 · 12 citations · Full text

Medicine, Oncology, Pharmacology +14

Amplified Ca²⁺ dynamics and accelerated cell proliferation in breast cancer tissue during purinergic stimulation

Mikkel B. Henningsen, Kezia Thorsted McWhan, Vibeke Secher Dam et al. · International Journal of Cancer · 2022 · 10 citations · Full text

Life Sciences, Oncology, Pharmacology +16